Cystatin C as a marker of renal function in older adults.
نویسندگان
چکیده
This article looks at the value of cystatin C in assessing renal function in older people. While it appears to be reliable and accurate, it is still relatively untested in most clinical settings and there is much to learn before its value in the day-to-day assessment of renal function can be determined.
منابع مشابه
Comparison of Serum Cystatin C and Creati-nine Levels to Evaluate Early Renal Function after Kidney Transplantation
Background: Accurate and rapid assessment of allograft function is essential in renal transplant recipients in order to detect allograft rejection and to monitor drug nephrotoxicity. We aimed to evaluate the usefulness of cystatin C as a marker of kidney allograft function in the early post-transplant period and to compare this value with that of conventional serum creatinine concentration. Met...
متن کاملبررسی مقایسه‌ای ارزش تشخیصی سیستاتین C و کراتینین سرمی در ارزیابی عملکرد کلیه پیوندی در بیماران گیرنده کلیه در دوران اولیه پس از پیوند
Background &Aim: Early detection of decreasing glomerular filtration rate (GFR) is critical to prevent graft rejection in post-transplantation period. Serum creatinine has several drawbacks as a marker of GFR, so serum cystatin C has been proposed as an alternative GFR marker. Thus, we prospectively evaluated the diagnostic value of cystatin C measurements compared with serum creatinine in t...
متن کاملComparative Assessment of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Cystatin C as Early Biomarkers for Early Detection of Renal Failure in Patients with Hypertension
Background: Hypertension is one the most common causes of chronic kidney disease (CKD). One of the major concerns in hypertensive patients is early detection of renal disorders. In the past, serum creatinine (Scr) concentration was used as a marker of kidney function, but it proffers a late reflection of reduced glomerular filtration rate. Cystatin C and neutrophil gelatinase-associated lipocal...
متن کاملSERUM CYSTATIN C AS A NEW MARKER OF GLOMERULAR FILTRATION RATE (GFR)
Cystatin C is a 13 KD basic protein that is a member of the cystatin superfamily of cysteine protease inhibitors. The cystatin C gene seems to be a house keeping gene, which is compatible with a stable production rate of cystatin C by most cells. This protein is freely filtered through the glomerulus and almost completely reabsorbed and catabolized by proximal tubular cells. Because of the...
متن کاملChanges in plasma cystatin C after renal transplantation and acute rejection in adults.
BACKGROUND Cystatin C has recently been proposed as an alternative marker of glomerular filtration rate. The diagnostic value of plasma cystatin C for the longitudinal assessment of kidney function after renal transplantation, however, has not been addressed. METHODS Renal function was evaluated in 30 adults receiving renal transplants (46 +/- 9 years, mean +/- SD) and in 56 healthy controls ...
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ورودعنوان ژورنال:
- Nursing standard (Royal College of Nursing (Great Britain) : 1987)
دوره 24 13 شماره
صفحات -
تاریخ انتشار 2009